The United States Patent and Trademark Office (USPTO) has granted a patent for the invention “Recombinant Pichia pastoris strain and method for producing active pediocin PA-1,” with patent number US11807856B2, issued on November 7, 2023, for the client IP GROUP, represented by the University of National University, Ho Chi Minh City.

Pediocin PA-1 is a peptide belonging to the bacteriocin group, exhibiting antibacterial activity, particularly against Listeria monocytogenes ATCC 13932 and some other bacterial strains. With the potential to combat pathogenic bacteria and foodborne contaminants, pediocin PA-1 can find applications in food preservation and the pharmaceutical industry.

The technology involving the recombinant Pichia pastoris strain is employed to enhance the expression of the pediocin PA-1 gene and secretion in the culture medium. This facilitates the easy retrieval and purification of pediocin PA-1 from the culture medium, reducing production costs and increasing efficiency.

With the granting of this patent, it is anticipated that the technology involving the recombinant Pichia pastoris strain and the method for producing active pediocin PA-1 will continue to be researched and developed. This opens up new opportunities for the application of pediocin PA-1 in food preservation and the pharmaceutical industry.

Patent information: [link to the patent on Google Patents]

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